Watch live: President Biden remarks on Cancer Moonshot Intiative

President Biden has promised to cut the cancer death rate in half over the next 25 years and improve the experience of patients and families, "ending cancer as we know it."

Cancer doctors, patients and researchers, not surprisingly, were thrilled by the "Cancer Moonshot" coming out of the Oval Office. But as with any big plan, the devil is in the details.

"How do you go from the locker room motivational speech to plays on the field? You have to connect the two," said Dr. David Tuveson, president of the American Association for Cancer Research.

It's realistic to dramatically cut cancer death rates, several experts said, based on the recent pace of advances and their expectations for the next few years. However, it will also require radical change.

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